In a study by Miller et al, with adults measuring pain in the first week of treatment. Kevin Miller et al. “A comparison of treatment impacts between Invisalign aligner and fixed appliance therapy during the first week of treatment.” American Journal of Orthodontics and Dentofacial Orthopedics. Volume 131, Issue 3, pp. 302. e1-302.e9, March 2007.
一項由 Align Technology 所贊助、針對成人 Class I 不拔牙的輕度到中度複雜齒列案例使用 SmartTrack 材質治療所進行的研究。David W. White, Katie C. Julien, Helder Jacob, Phillip M. Campbell and Peter H. Buschang, Discomfort associated with Invisalign and traditional brackets: A randomized, prospective trial. The Angle Orthodontist Nov 2017, Vol. 87, No. 6 pp. 801-808
Gu, J et al. Evaluation of Invisalign treatment effectiveness and efficiency compared with conventional fixed appliances using the Peer Assessment Rating index. Am J Orthod Dentofacial Orthop February 2017;151:259-66; and Buschang, P et al. Comparative time efficiency of aligner therapy and conventional edgewise braces. Angle Orthodontist, Vol 84, No 3, 2014
*Invisalign patients require on average 30% fewer doctor visits than fixed appliance patients.Buschang et al; Comparative time efficiency of aligner therapy and conventional edgewise braces. Angle Orthod 1 May 2014; 84 (3): 391–396. Borda et al; Outcome assessment of orthodontic clear aligner vs fixed appliance treatment in a teenage population with mild malocclusions. Angle Orthod 1 July 2020; 90 (4): 485–490.
